Most of your critical application traffic does not reach your physical network infrastructure anymore: it is carried by virtual switches inside your VMware farm.
To run diagnostics, you need to capture this virtual traffic: how can you do that?
VMware VDS (Virtual Distributed Switch) natively integrates capabilities to mirror traffic; this feature can be used by network analysis device for troubleshooting purposes.
This short video shows how you can set up a VMware vSphere Distributed Switch and SkyLIGHT PVX to visualize traffic & performance metrics between virtual machines.